Product ID:ZANOSAR STERILE POWDER
MSDS Date:01/01/1994
FSC:6505
NIIN:00D020067
MSDS Number: BVGXQ

Emergency Phone: 616-323-6722 (24 HOURS)

Info Phone: 30 PM)

Cage: EO390

Telephone: 30 PM)

Cage: EO390

STREPTOZOCIN

CAS: 18883-66-4

RTECS: LZ5775000

Fraction By Weight: < 100%

NON-HAZARDOUS INGREDIENTS

Fraction By Weight: < 100%

LD50 LC50 Mixture:ORAL LD50 (RAT): 5150 MG/KG
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:RENAL (KIDNEY) TOXICITY WHICH MAY BE
SEVERE OR FATAL. ALSO MAY CAUSE NAUSEA, VOMITING, ALTERATIONS IN
LIVER FUNCTION. MAY AFFECT GLUCOSE METABOLISM. IRRITANT TO TISSUES
AND MAY LEAD TO LOCAL ULCERATIO N AND NECROSIS AND MAY CAUSE
IRRITATIONTO EYES AND SEVERE IRRITATION TO SKIN.
Explanation of Carcinogenicity:THIS COMPOUND CONTAINS NO INGREDIENTS AT
CONCENTRATIONS OF 0.1% OR GREATER THAT ARE CARCINOGENS OR SUSPECT
CARCINOGENS.
Effects of Overexposure:RENAL TOXICITY, ALTERED LIVER FUNCTION, NAUSEA,
VOMITING, CHANGES IN GLUCOSE METABOLISDM, ULCERATION AND LOCAL
NECROSIS, EYE IRRITATION, SKIN IRRITATION.
Medical Cond Aggravated by Exposure:NONE SPECIFIED BY MANUFACTURER.

First Aid:EYES: FLUSH WITH WATER FOR 15 MINUTES WHILE HOLDING EYELIDS
OPEN. GET MEDICAL ATTENTION. SKIN: REMOVE CONTAMINATED CLOTHING.
WASH WITH SOAP AND WATER. IF IRRITATION PERSISTS, GET MEDICAL
ATTENTION. IN HALATION: REMOVE TO FRESH AIR. RESTORE BREATHING. GET
MEDICAL ATTENTION. INGESTION: CONTACT A PHYSICIAN OR POISON CONTROL
CENTER IMMEDIATELY.

Flash Point:NONFLAMMABLE
Lower Limits:NOT GIVEN
Upper Limits:NOT GIVEN
Extinguishing Media:WATER, DRY CHEMICAL, CARBON DIOXIDE
Fire Fighting Procedures:FIRE FIGHTERS SHOULD USE NIOSH APPROVED SCBA &
FULL PROTECTIVE EQUIPMENT WHEN FIGHTING CHEMICAL FIRE.
Unusual Fire/Explosion Hazard:AS WITH ALL FINELY DIVIDED ORGANIC
POWDERS, IT IS ADVISABLE TO ELIMINATE EXPLOSION HAZARDS BY METHODS
SUCH AS GROUNDING MECHANICAL EQUIPMENT, ETC.

Spill Release Procedures:REMOVE IGNITION SOURCES. CONTROL GENERATION OF
DUST/VAPORS. PROVIDE VENTILATION AND PERSONAL PROTECTIVE GEAR. KEEP
OUT OF DRAINS, SURFACE WATER, GROUNDWATER AND SOIL. VACUUM OR SCOOP
SPILLED MATERIAL AND PLACE IN CONTAINER.
Neutralizing Agent:NONE SPECIFIED BY MANUFACTURER.

Handling and Storage Precautions:AVOID CONTACT WITH SKIN ,EYES AND
CLOTHING. WASH THOROUGHLY AFTER HANDLING. STORE IN A COOL, DRY
PLACE AND PROTECT FROM LIGHT.
Other Precautions:AVOID SKIN CONTACT. LAUNDER CONTAMINATED CLOTHING
BEFORE REUSE. KEEP OUT OF REACH OF CHILDREN.

Respiratory Protection:APPROVED RESPIRATOR IF THERE IS OPPORTUNITY FOR
SPLASH, MIST OR AEROSOL GENERATION.
Ventilation:LOCAL EXHAUST AND MECHANICAL (GENERAL) VENTILATION TO
MAINTAIN EXPOSURE LEVELS.
Protective Gloves:RUBBER
Eye Protection:NOT REQUIRED
Other Protective Equipment:AN EMERGENCY EYE WASH STATION AND SHOWER
SHOULD BE AVAILABLE.
Work Hygienic Practices:WASH WITH SOAP AND WATER AFTER HANDLING PRODUCT
AND BEFORE EATING DRINKING OR SMOKING.
Supplemental Safety and Health
HOSPITAL PERSONNEL PERPARING OR ADMINISTERING PRODUCT SHOULD WEAR LATEX
GLOVES OR SURGICAL RUBBER GLOVES, SAFETY GLASSES, A CLOSED FRONT
GOWN WITH KNIT CUFFS AND MASKS. PREPARATION SHOULD BE DONE IN A
CLASS II LAMINAR FLOW BIOLOGICAL SAFETY CABINET WITH EXHASUT AIR
DISCHARGED EXTERNAL TO THE ROOM ENVIRONMENT.

HCC:N1
Boiling Pt:B.P. Text:NOT GIVEN
Melt/Freeze Pt:M.P/F.P Text:NOT GIVEN
Vapor Pres:NOT GIVEN
Vapor Density:NOT GIVEN
Spec Gravity:NOT GIVEN
Evaporation Rate & Reference:NOT GIVEN
Solubility in Water:SOLUBLE
Appearance and Odor:WHITE POWDER PACKAGED IN VIALS

Stability Indicator/Materials to Avoid:YES
NONE SPECIFIED BY MANUFACTURER.
Stability Condition to Avoid:NONE SPECIFIED BY MANUFACTURER.
Hazardous Decomposition Products:NONE SPECIFIED BY MANUFACTURER.
Conditions to Avoid Polymerization:TEMPERTURES ABOVE 4C.

Waste Disposal Methods:PREVENT WASTE FROM CONTAMINATING SURROUNDING
ENVIRONMENT. DISCARD ANY PRODUCT, RESIDUE, DISPOSAL CONTAINER OR
LINER IN ACCORDANCE WITH ALL FEDERAL, STATE AND LOCAL REGULATIONS.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.